HLA molecules scoop these up and shuttle them to the cell’s surface for surveilling T cells to sample in search of foreign invaders. A TCR can detect tiny amounts of these molecules; some researchers ...
These two general immune response findings, immune response at baseline and increasing immune response over time, were also observed in the Phase IIb clinical trial for HLA-A*02 only patients. These ...
In a recent article published in Nature Cancer, a multi-institutional research team led by The University of Osaka describes ...
"We needed to make a new type of cell, because we were trying to target specific antigens called peptide-HLA (human leukocyte ... that are displayed on the cell surface by peptide-holding proteins ...
A new report in The EMBO Journal describes the transfer of HLA-G molecules by trogocytosis from tumour cells to activated natural killer (NK) cells, which might be a mechanism of protection for ...
Likewise, HLA-A2 transgenic mice immunized with ... co-expression of RT2 and pep23 determinants on the surface of the same presenting cell. Pep23 is a promiscuous epitope that can also be ...