PRMT1, arginine methyltransferase 1; CBP, CREB binding protein; HDAC1, histone deacetylase 1; SIRT3, sirtuin 3; HAT1, histone acetyltransferase 1. Chronic hepatitis B virus (HBV) infection continues ...

oral TLR7 agonist RG7854 and HBV core protein allosteric modulator RG7907. Dicerna is retaining an option to co-fund pivotal development of the product globally, which would entitle the company to ...

Conclusion: Both core promoter and YMDD motif mutation(s ... Analysis of lamivudine-resistant strains of HBV DNA has invariably shown nucleotide substitutions that induce amino acid changes ...