New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...

Researchers are shedding new light on the link between diet and cancer growth—especially the way certain fats may fuel ...

Diabetes results from elevated blood glucose ... This not only adds to our understanding of biology and signaling pathways in cells, but, more importantly, it is leading to exciting new ...

Several lines of evidence link metabolic dysregulation to late-life neurodegenerative diseases. The altered glucose ...

Currently, more than 500 million people worldwide suffer from diabetes, and the number ... and fibrosis through the TGF-β/Smad3 signaling pathway, worsening DKD. The activation of the NLRP3 ...

Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...