Bispecific antibodies (bsAbs) exert their function through diverse strategies including T-cell engagement for immune-mediated tumor cell killing, dual immune checkpoint inhibition to enhance immune ...

New topline data from the MINT trial (NCT04524273), which is investigating inebilizumab in patients with generalized myasthenia gravis who are acetylcholine receptor (AChR) antibody or muscle ...

Ligand-receptor partners mediating these stages in different contexts are discussed from recent Drosophila and mouse studies. Signaling cues include phospholipids, small neurotransmitters, ...

More than 40 Drosophila melanogaster genes have been ... A disadvantage is that it is labour intensive, and antibody labelling can be difficult. Many preparations are commonly used for ...

The elevated levels of TfR1 expression on malignant cells, together with its extracellular accessibility, ability to internalize, and central role in cancer cell pathology make this receptor an ...

We find that Drosophila employ an olfactory-immune cross-talk to tune a specific cell type, the lamellocytes, from hematopoietic-progenitor cells. We show that neuronally released GABA derived upon ...

Here, we identify a zinc-finger transcription factor Hindsight (Hnt) as the first transcription factor regulating follicle’s competency for ovulation in Drosophila ... expression in all follicle cells ...