The hypothalamus is a small but critical region at the base of the brain that controls the autonomic nervous system, ...

Delicious and extremely palatable food can increase the tendency of hedonic eating, where one consumes food for the sole purpose of deriving pleasure instead of the body's energy needs. Hedonic eating ...

Dopamine detoxing addresses overstimulation by abstaining from high-dopamine activities, potentially improving mental health and emotional resilience.

A previously overlooked dopamine-producing brain circuit drives hedonic eating, or eating for pleasure, according to a new study in mice. The findings offer insights into how GLP-1 agonist drugs ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently diagnosed with Parkinson’s Disease ...

A cruel consequence of advanced cancer is the profound apathy many patients experience as they lose interest in ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts ...

As cancer progressed, mice still pursued easy rewards but quickly abandoned tasks requiring greater effort. Meanwhile, we ...

The modified LSD, which they named JRT, did just that—and more. It stimulated neurons to sprout new dendritic branches and ...