The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Ultimately, the maturation, dimerization, activation, time of existence (referred to as half-life), and degradation are all tightly regulated by either ERBB receptors themselves or other proteins ...

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their ...

Small molecule inhibitor of survivin dimerization for the treatment of solid tumors. Survivin, a homodimeric member of the Inhibitor of Apoptosis Protein (IAP) family, is required for cancer cell ...