The Chat Completion API is still available separately. However, OpenAI recommends using the Responses API for new integrations, even if agent capabilities are not yet required.

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The difference between Assistants and Agents By enabling GPT-4 to interact and work with existing apps and services, the Assistants API creates a new paradigm for AI-assisted tasks.

Using the Assistants API, OpenAI customers can build an “assistant” that has specific instructions, leverages outside knowledge and can call OpenAI generative AI models and tools to perform tasks.