CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

There is an urgent need for precision immunotherapy strategies that simultaneously target both tumor cells and immune cells ...

Explore a high-throughput picodroplet-based method for CAR-T cell functional validation that enables rapid, single-cell ...

Triple-negative breast cancer, an aggressive type of breast cancer, accounts for 10% of all breast cancer cases in the United ...

Antengene Corporation Limited ("Antengene", SEHK: 6996.HK), a leading innovative, commercial-stage global biopharmaceutical company dedicated to discovering, developing and commercializing ...

State Key Laboratory of Flexible Electronics (LoFE) & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), School of Chemistry and Life ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses against metastatic pancreatic cancer.

1School of Basic Medical Science, Southern Medical University, Guangzhou, China. 2Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. 3Zenith Institute of ...

In addition, the cytotoxic potential of the redirected T cells was unaffected ... anti-human CD3-FITC and anti-human CD8-APC (all Miltenyi Biotec GmbH). Immunofluorescence staining of cell surface ...

cancer cell biological assays, and high-content phenotypic screening to identify potential regulators, and function, of nuclear fascin, and the consequences of maintaining too high levels of fascin in ...