Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

present a large placental methylation database as a tool to explore ... Here, the authors generate a comprehensive map of accessible chromatin by integrating the ATAC-seq data of 12 major maize ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. GA, UNITED STA ...

A new study highlights the placenta’s role in neuropsychiatric development, showing that DNA methylation influences gene ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

This article explores 6-base genome sequencing and how it is empowering researchers to expand their studies to include both ...

By focusing on chromatin-modifying enzymes ... Key epigenetic mechanisms—such as DNA methylation, histone modifications, and the involvement of noncoding RNAs—regulate cccDNA activity. For example, ...

The second act of a popular reprogramming factor could maximize the potential of iPSCs in research and regenerative medicine.

Fluorescence microscopy was used to assess sperm chromatin packaging and DNA fragmentation. CMA3 staining was employed to determine the level of sperm protamination. Statistical analyses ...

Department of Physics, North Carolina State University, Raleigh, North Carolina 27607, United States Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27607, ...

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