Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.

Therefore, chromatin is further coiled into an even ... Part of the problem lies in the fact that electron microscopy is perhaps the best way to visualize packaging, but individual nucleosomes ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this ...

Therefore, understanding the chromatin structure-based mechanisms that regulate the use of the genetic information is crucial for designing new therapeutic strategies. Based on advanced cryo-electron ...

During interphase, individual chromosomes are not visible, and the chromatin appears diffuse ... developed for visualizing spindles using electron microscopes (Mitchison & Salmon, 2001).

Cell and Molecular Biology reveals the molecular basis of both normal and abnormal cell and tissue biology, focusing on cancer, regulation of gene expression, epigenetics of chromatin ... NMR, ...

Using a combination of advanced genetic tools, 3D electron microscopy, and artificial intelligence, Scripps Research scientists Marco Uytiepo, Anton Maximov, Ph.D., and colleagues reconstructed a ...

To better understand how chromatin remodeling works, scientists at St. Jude Children’s Research Hospital used cryo-electron microscopy (cryo-EM) to obtain fine structural details of a human ...