proved to be the rate-controlling enzyme in cholesterol synthesis. On the basis of these facts, I speculated that a cholesterol-synthesis inhibitor, particularly a HMG-CoA reductase inhibitor ...

Cholesterol synthesis is an ATP-intensive process that involves nearly thirty enzymatic reactions and over fifteen proteins; therefore, any disruptions in genes or enzymes involved in cholesterol ...

The researchers observed that several genes associated with cholesterol metabolism were significantly downregulated when PIN1 was knocked out. Daniel Eduardo Gomez, a physician scientist at the ...