Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between ...

Scientists are looking for answers about how these confounding trips, known as metastases, occur throughout the human body ...

Cancer metabolism refers to the alterations in cellular metabolism pathways that are evident in cancer cells compared with most normal tissue cells. Metabolic alterations in cancer cells are ...

Scientists discovered that cancer cells cooperate to obtain nutrients by secreting an enzyme, CNDP2, which breaks down proteins into shared amino acids. Blocking CNDP2 with the drug bestatin or ...

Century Therapeutics has joined the onslaught of cell therapy biotechs taking hits, discontinuing a phase 1 cancer study to turn its focus toward autoimmune diseases. The move isn’t shocking ...

Scientists have supercharged CAR-T therapy, making it more powerful against elusive cancer cells that usually escape detection. This innovation, called ALA-CART, helps the immune system better ...

By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight ...

In this protocol, we detail a seven-stage differentiation methodology for generating pancreatic delta cells (SC-delta cells) from human pluripotent stem cells (hPSCs). In the first step, definitive ...

However, the potential roles of MAIT cells in anticancer immunity or cancer progression and their significance in shaping clinical outcomes remain largely unknown. In this study, we analyzed publicly ...

We refer to these cells as tumorigenic cells, or cancer-initiating cells, because they consistently formed tumors, whereas other cancer cell populations were depleted of cells capable of tumor ...