1 Division of Endocrinology, Diabetes & Metabolism, Assistant Professor ... Glucocorticoid receptor antagonists (mifepristone) and somatostatin receptor antagonists (pasireotide) represent ...

Trial 3) somatostatin infusion at 100 ng/kg/min (same as during ... Taken together, these findings provide evidence that GDF15 is a hepatokine and related to energy metabolism. However, of relevance ...

The interplay between glucagon, insulin and somatostatin in the regulation of glucagon secretion ... there are significant side effects that result from impaired hepatic metabolism and potentially ...

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical ...

Somatostatin analogues are medicines that stop your body from making too many hormones. Some neuroendocrine tumours (NETs) make large amounts of hormones. This can cause symptoms. Somatostatin ...

Melbourne-based scientists have, for the first time, discovered how to "switch off" a molecule which is one of the top ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

As part of The Wistar Institute's Melanoma Research Center, the Villanueva lab pursues new ways to overcome the challenge of melanoma drug resistance. In this paper, the group took aim at melanomas ...

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

Molecular imaging, including somatostatin receptor scintigraphy but more so PET with specific tracers, such as C 11-5HTP or Ga 68-DOTA octreotate, will improve staging and follow-up of therapy in ...

Insulin-like growth factor (IGF) 1 is a member of a family that is involved in growth, development, cell differentiation, and metabolism. IGF1, IGF2 and insulin act primarily through tyrosine ...