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Small Molecule Therapeutic Discovery, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Their dysregulation has been implicated in numerous diseases, particularly cancer. This is where kinase inhibitors come into play. Kinases have become one of the most extensively targeted enzymes in ...

ORLANDO, Fla. — Of the 12 biologics in four drug classes approved for treating psoriasis in the United States, interleukin 23 (IL-23) inhibitors might be exceptional, particularly if used early ...

Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland ...

The newly released Ninja Swirl by Creami is making a huge splash in the ice cream world and I've found the best place for it: the office. After all, nothing helps boost company morale better ...

With approximately 40mg of DIM per application, this cream is a powerful aromatase inhibitor that helps the body metabolize excess potent estrogens. We love that the SMNutrition DIM Cream ...

As our knowledge about aromatase inhibitors and their side effects has expanded, questions remain unanswered with regards to their influence on cognition. Future study designs evaluating cognitive ...

A novel, allosteric and highly potent USP1 inhibitor, LAE120 exhibits robust tumor inhibitory activity across various xenograft models Significantly accelerated the progress of drug discovery ...