The availability of suzetrigine may represent a critical step in addressing the nation’s pain management crisis. While questions remain about its cost, adoption, and long-term efficacy, its novel ...

The principal therapeutic action of morphine is analgesia. The precise mechanism of action is not known but the effects are thought to be mediated through opioid-specific receptors located in the CNS.

FDA approval of a novel non-opioid analgesic will hopefully address the needs of many patients with acute pain and improve clinical outcomes and QOL.

although the exact mechanism of analgesic action remains unknown. Serious and life-threatening risks from use of Codeine Sulfate tablets: Addiction, abuse, and misuse; Life-threatening respiratory ...

Voltage-gated Na + channels propagate action potentials along neurons and ... v 1.7α subunit can lead to erythermalgia and congenital analgesia, respectively. Agents such as carbamazepine ...

Researchers have made new discoveries about aspirin’s mechanism of action and cellular targets. Their findings suggest potential interplay between cyclooxygenase enzyme, or COX, and indoleamine ...

In a recent study reported in Pain, researchers show for the first time that the mechanisms that underlie ... element of the effects of an analgesic in patients with early-stage Alzheimer's ...