This action promotes cholinergic and non-adrenergic neurotransmission by enteric neurons, leading to increased peristaltic reflex, intestinal secretions, and overall gastrointestinal motility. Nora ...

Neurons are cells found in your brain and central nervous system that tell your body how to behave. There are approximately 86 billion neurons in the human brain. Interestingly, your gut contains ...

1Department of Medicine, Columbia Center for Human Development, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York. 2Herbert Irving Comprehensive ...

Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...

The activation of adrenergic receptors on neurons and astrocytes, and pleiotropic effects has the potential to not only improve cognition, but to slow disease progression." ...

Studies have shown that dysfunction and downregulation of adrenergic receptors (ARs) are often implicated in these shock conditions; for example, their density is shown to be decreased in hypovolemic ...

In addition, GABA-stimulated astrocytes can affect the differentiation and maturation of neurons. During early development ... or through bestrophin (Best1). α-2 adrenergic receptors also modulate the ...

This mechanism starts when the α1-adrenergic receptor, a protein at the surface of the cell, detects noradrenaline molecules. However, on its own, the α1-adrenergic receptor is unable to create an ...

Therefore, we postulate that adrenergic C1 neurons are in synaptic contact with the pFRG region to recruit expiratory muscles via glutamatergic signaling in order to regulate breathing during hypoxia ...