Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule
Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane ...
Heat-activated receptor could unlock new pain therapies
Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better ...
argenx Highlights FcRn Leadership with Long-term Data and Transformational Patient Outcomes at the American Academy of Neurology 2025 Annual Meeting
Largest safety data set on FcRn blocking demonstrates consistent, favorable safety profileof VYVGART and VYVGART HytrulogMG patients on VYVGART ...
Medscape14d
Divergence of Allosteric Effects of Rapacuronium on Binding and Function of Muscarinic Receptors
We examined the influence of rapacuronium on acetylcholine (ACh) binding to and activation of individual subtypes of muscarinic receptors expressed in Chinese hamster ovary cells to determine its ...
Neuroscience News26d
How Ketamine Binds to Brain Receptors to Alter Mood
A distinct variant, the tri-heteromeric receptor, comprising glycine-binding GluN1 and two types of glutamate-binding GluN2 subunits, exhibits unique pharmacological characteristics, notably enhanced ...