The EMBO Journal13h
A new class of capsid-targeting inhibitors that specifically block HIV-1 nuclear import
A major unresolved challenge to curing HIV-1 is its presence in the nucleus of infected cells. This study reports on new ...
The EMBO Journal5d
Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males
Evidence suggests mitochondrial homeostasis plays a role in autism spectrum disorders (ASDs), but the causal relationships ...
The EMBO Journal2d
Cellular senescence, p21, and the path to fibrosis
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
The EMBO Journal12d
Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
The EMBO Journal13d
Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury
The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...
The EMBO Journal7d
BATokines in metabolic liver disease: good cops or bad cops?
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et ...
The EMBO Journal7d
Time bomb
The time bomb of misinformation and disinformation will have exploded, taking with it our ability to think for ourselves.
The EMBO Journal13d
A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
The EMBO Journal6d
A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The intracellular bacterial pathogen Coxiella ...
The EMBO Journal8d
Combining systems and synthetic biology for in vivo enzymology
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The physiological significance of enzymatic ...