Madness has gotten off to an exciting start. South Carolina and Notre Dame both flexed their dominance with blowout victories, Kentucky survived an upset scare against Liberty, and Oregon became the first double-digit seed to advance with an overtime victory over freshman phenom Mikayla Blakes and Vanderbilt.

The Madness has arrived. Tuesday night the 2025 men’s NCAA tournament kicks into gear, with two of the First Four games coming from Dayton, Ohio. In the first game No. 16 St. Francis (PA) will square off with No.

The top betting favorites as the tournament begins: Florida and Duke are listed as co-favorites (+325), according to BetMGM Sportsbook. Auburn (+425) and Houston (+600) are next. The first round tipped off on Thursday and will continue Friday, stretching from Providence, Rhode Island, to Seattle and busting brackets from coast to coast.