Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.

A new scientific review published in Neuropharmacology explores how the environment interacts with brain biology in shaping personality disorders. By examining molecular, neurochemical, and metabolic ...

A systematic review published in Discover Oncology explores the anticancer efficacy of medicinal plant extracts in treating Oral Squamous Cell Carcinoma (O | Plants And Animals ...

Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

Blagosklonny goes on to write that even though rapamycin may reverse some manifestations of aging, it is more effective at slowing down aging than reversing it. Thus, rapamycin could be most effective ...

Thank you for joining us to review Celcuity's fourth ... Three interconnected signaling pathways: estrogen's cyclin D1, CDK4/6 and PI3K-AKT-mTOR pathways promote this disease.

This Research Topic includes four original research articles and two reviews, shedding light on key ... One of the most studied molecular pathways in Alzheimer's disease (AD) is the mTOR signaling ...

WAYNE, Pa., March 31, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: PVLA) Palvella Therapeutics, Inc. (Palvella or “the Company”), a clinical-stage biopharmaceutical company focused on developing and ...

About Cutaneous Venous Malformations Cutaneous VMs are a rare genetic disease caused by mutations in genes that cause overactivation of the PI3K/mTOR signaling pathway, leading to dysfunctional veins ...

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu 611137, China School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China Key Laboratory of ...