Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...
In this review, we summarize the current literature suggesting ... mTOR-S6K1 signaling pathway inhibits AMPK activation through inactivation of TAK1. Figure 2. AMPK-mTOR signaling pathways during Mtb ...
Similarly, the PI3K/AKT/mTOR signaling pathway is also known to promote GC tumor progression ... scope manuscript to a more suitable section or journal at any stage of peer review. Frontiers' Research ...
mTOR plays a pivotal ... integrates three critical pathways—cellular glutamine-level control, P27KIP1 protein stability, and noncanonical lysosomal-translocation of P27KIP1—to generate a robust ...
In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...
This important study investigates the signaling pathways regulating retinal regeneration ... These findings were relatively consistent with our previous findings, where mTOR activation was observed ...
A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...
Therefore, dust fall microplastics inhibited autophagy and induced apoptosis via activating the PI3K/Akt/mTOR pathway, increasing the Bax/Bcl-2 and Cleaved Caspase-3/Caspase-3 ratios. Here we provide ...
In “Cerebral Entanglements,” Allan J. Hamilton argues that new imaging technologies give us unprecedented access — with revolutionary implications. By Deborah Blum “Saturday Night Live ...
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