Molecular Mystery Solved: “Useless” RNA Segments Actually Help Cells Fight Stress
This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...
'Junk' RNA segments found to play role in protein production and cell stress response
Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...
Hosted on MSN22d
Researchers Complete Synthetic Yeast Chromosome, Advancing Genome Engineering
This species of yeast is widely used in research and industry ... Additionally, a transfer ribonucleic acid (tRNA) neochromosome carrying 17 relocated tRNA genes was introduced to compensate ...
Nature17d
The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I
The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively ...
technologynetworks29d
Scientists Complete the World’s First Synthetic Yeast Genome
Macquarie University researchers and an international team have completed the first synthetic yeast genome, a breakthrough in synthetic biology. Published in Nature Communications, this achievement ...
Science Daily29d
Final synthetic yeast chromosome unlocks new era in biotechnology
and a new-to-nature tRNA neochromosome. Using cutting-edge genome-editing techniques, including the CRISPR D-BUGS protocol, the team identified and corrected genetic errors that impacted yeast ...
Phys.org29d
Final synthetic yeast chromosome completed, paving way for biotech advances
and a new-to-nature tRNA neochromosome. Using cutting-edge genome-editing techniques, including the CRISPR D-BUGS protocol, the team identified and corrected genetic errors that impacted yeast ...
GEN29d
First Synthetic Eukaryotic Genome Completed
and a new-to-nature tRNA neochromosome. Using genome-editing techniques, including the CRISPR D-BUGS protocol, the team identified and corrected genetic errors that impacted yeast growth.
University of Manchester1y
Scientists one step closer to re-writing world’s first synthetic yeast genome, unravelling the fundamental building blocks of life
The tRNA neochromosome is used to house and organise all 275 nuclear tRNA genes from the yeast and will eventually be added to the fully synthetic yeast where the tRNA genes have been removed from the ...