Sigma-Aldrich), and Alexa Fluor 488-conjugated goat antimouse secondary antibody (1:250, R37120; Invitrogen). Quantification of Pearson correlation coefficient for the colocalization of VE-cadherin ...

Primary cultures were trypsinised and endothelial cells were isolated by paramagnetic beads armed with monoclonal antibody to CD31 ... expressed von Willebrand factor, CD31, and VE-cadherin; and bound ...

Following rinsing with TBST three times, the PVDF membranes were incubated with secondary antibodies (EMAR, Beijing, China) at room temperature for 1 h, and antibody binding was ... a tight junction ...

The vimentin primary antibody was diluted to 1:200 in 3% bovine serum albumin ... confirmed in future experiments by using various markers of tight junction (i.e., VE-cadherin and N-cadherin). Dextran ...

a novel antibody-drug conjugate (ADC) targeting cadherin-17 (CDH17). The data highlight SOT109's promising activity and tolerability profile across multiple disease models, reinforcing its ...

A TROP2-directed antibody-drug conjugate, DB-1305/BNT325, demonstrated durable activity in patients with previously treated ovarian cancer in a first-in-human trial. These results were presented at ...

The current state of treatment for geographic atrophy is marked by two approved therapies that slow GA progression: ...

There will be a four-day celebration of the 80th anniversary of VE Day, including a flypast, concert and a Westminster Abbey service, the government has announced. The commemorations, marking 80 ...

It was one of the biggest moments of celebration in the 20th century – though VE Day also provided an opportunity to reflect on everything that was lost. Eight decades on, the government has ...

The VE Day celebrations will kick off as part of the early May Bank Holiday. Secretary of State for Culture, Media and Sport Lisa Nandy announced the plans, calling it the perfect way to “pay ...