For example, a classic DILI pair, highlighted by the IQ MPS consortium, are troglitazone and pioglitazone. Troglitazone was the first marketed compound for type 2 diabetes. However, it was ...

troglitazone, and the newer biologic agents, such as adalimumab, alefacept, efalizumab, etanercept, and infliximab). In a recent Japanese Society for Psoriasis Research analysis of 28,628 cases ...

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, affecting approximately 6% of this population. [1] The clinical issues in PCOS relate to ...

Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings and market withdrawals, therefore it is important to identify mitochondrial toxicity ...

ABSTRACT: In this paper, we aim to highlight the barriers to knowledge when investigating relics. This occurs because these objects interest different groups (Christians, Agnostics, Atheists, and ...