Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.

Cardiac macrophages in newborn mice promoted heart cell proliferation after injury, offering a potential approach to ...

Platelets release a molecule called thromboxane A2 (TXA2), which shuts down T cell activity, making it easier for cancer to take root in new locations. In the new study, researchers screened 810 ...

They found that ARHGEF1 is switched on when T cells are exposed to a clotting factor called thromboxane A2 (TXA2) – an unexpected finding for the scientists. TXA2 is produced by platelets in the ...

A2 thromboxane A2; Nrf2, nuclear factor erythroid 2 related factor 2. ARE, antioxidant response element; ERK, extracellular regulated protein kinases; JNK, c-Jun N-terminal kinase; P38, ...