Raluka Serban, the first Cypriot player to win a WTA main-draw match, found a superbly sharp angle on the run to deny top seed Marie Bouzkova with a pass in the Copa Colsanitas Zurich second round.
Top seed Sebastian Baez enters the Bucharest fray, taking on Gabriel Diallo. Plus, Daria Kasatkina meets Lauren Davis in Charleston, while fourth seed Emma Navarro plays Hailey Baptiste.
Czech teenager Jakub Mensik upset Novak Djokovic 7-6 (7/4), 7-6 (7/4) to win the Miami Open at Hard Rock Stadium on Sunday, denying the Serb his 100th career title.