it is essential to consider things like the expression of the target and the target organ and whether the models selected express the target required. It is also important to consider whether the ...

In contrast to infection, the antigens that these cells recognise are processed from proteins within the target organ and this drives a chronic inflammatory process that disrupts the normal function ...

Macrophages interact with T cells in order to bring about T cell activation in target organs, and are themselves activated by inflammatory messenger molecules (cytokines) produced by the T cells.