However, on infiltrating the sAH liver, these neutrophils are stimulated by the inflammatory environment, including mediators such as TNF-α and IL-1β, to produce high levels of IL-8.

Intravital imaging reveals that dermal monocytes orchestrate neutrophil transepidermal migration through hair follicles in skin inflammation via TNF-α and CXCL2, driving enhanced MMP-9 expression ...

An increased risk of both invasive and superficial fungal infections was observed among patients who received TNF-α inhibitors for various conditions.

55 11 3061 7457 Fax: +55 11 3081 7190 [email protected] Establishing that TNF-α plays an important role in the pathogenesis of several immune-mediated inflammatory diseases led to the development of ...