Data from DELIVER and ACHIEVE Clinicals Trial to be Presented -- Presentation on ACHIEVE Trial in DM1 and Company Symposium to Feature Data on ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

Faculty of Life Sciences, Department of Pharmaceutical Sciences, Laboratory of Macromolecular Cancer Therapeutics (MMCT), University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

This important study reports on PI3KR mutations and a paradoxical mechanism of PI3KR signaling. The strength of evidence for the study is mostly convincing, as conclusions are supported by a variety ...

1129–5923C>G splice mutation was significantly enriched in patients with severe 5-FU-related toxicity (9.1%; 66 patients) compared with patients without toxicity (2.2%; 137 patients), confirming ...

Pre-mRNA splicing is carried out by the spliceosome which contains more than 100 proteins and 5 U snRNAs. The accuracy and efficiency of the spliceosome are often compromised in many human cancers.

Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder Researchers studying brain cells from Huntington's patients show that the ...

Video: Broad Institute of MIT and Harvard At a glance: Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though patients are born ...

Researchers in the group of Dr. Myriam Charpentier discovered a mutation in a gene in the legume Medicago truncatula that reprograms the signaling capacity of the plant so that it enhances ...