ahajournals.org23d
Protein Drug Targets for Abdominal Aortic Aneurysm and Proteomic Associations Between Modifiable Risk Factors and Abdominal Aortic Aneurysm
sphingomyelin phosphodiesterase 1; THBS2, thrombospondin‐2; TNFSF12, tumor necrosis factor ligand superfamily member 12; UBE2C, ubiquitin‐conjugating enzyme 2C; and USP15, ubiquitin specific peptidase ...
Frontiers17d
Editorial: Alzheimer's disease: new insights into biomechanisms and therapeutic target
AD brains exhibited higher levels of sphingosine (Sph), total ceramide 1-phosphate (Cer1P) and total ceramide (Cer), while higher levels of sphingomyelin (SM) exclusively in Cerad-B brains, which ...
Taiwan News24d
3Z Pharmaceuticals Publishes Breakthrough Study on Shared Metabolic Pathways in ADHD Therapeutics
REYKJAVIK, Iceland, Feb. 24, 2025 /PRNewswire/ -- 3Z Pharmaceuticals, a CNS-focused therapeutic development specialist, today announced the publication of a groundbreaking study in The Journal of ...
C&EN22d
Phase Separation Clustering of Poly Ubiquitin Cargos on Ternary Mixture Lipid Membranes by Synthetically Cross-Linked Ubiquitin Binder Peptides
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Ubiquitylation is involved in various physiological processes, such as signaling and ...
Frontiers24d
L-serine metabolic regulation and host respiratory homeostasis
L-Serine, a non-essential amino acid (NEAA), can be obtained through diet or in situ synthesis. Functionally, L-serine not only serves as the precursor of other amino acids, lipids, and nucleotides, ...
Medscape24d
Analytical chemistry
One-Pot Three Carbon Dots with Various Lifetimes Rooted in Different Decarboxylation Degrees for Matrix-Free, Anti-Oxygen, and Time-Resolved Information Encryption and Cellular Imaging.
Scientific Research Publishing20d
Skin Hydration Augmentation Following Solar Protective and Repair Skincare Regimen ()
2 Clinica Tanaka Plastic, Reconstructive Surgery and Anti-Aging Center, Matsumoto, Japan. As for most of the human body, water is a critical component to keep the skin and especially the SC, fully ...
thorax.bmj16d
Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
5 Department of Medicine, Faculty of Medicine, University of Valencia, Valencia, Spain 6 Department of Pharmacology, Faculty of Medicine, University of Valencia, Valencia, Spain Correspondence to Dr ...
gut.bmj17d
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Conclusion Our ...