Mitochondria produce some of the proteins they need themselves—with the help of special protein factories called mitoribosomes, which consist of RNA and proteins. Researchers in Göttingen have ...

Dr. Ma's team found that chemical modification of RNA (called RNA methylation) regulates mitochondrial function. Mitochondria ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Similarly, a homoplasmic mutation in a mitochondrial genome-encoded ribosomal RNA, called RNR1, causes postlingual deafness (deafness that occurs after three years of age, when a child has already ...

Blum, B., Bakalara, N. & Simpson, L. A model for RNA editing in kinetoplastid mitochondria: RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60, 189–198 (1990).

Cystinuria is the most common inheritable cause of kidney stone disease, characterized by impaired reabsorption of cystine and dibasic amino acids in ...

Mitochondrial deoxyribonucleic acid (mtDNA ... More information: Shigeru Matsuda et al, TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA ...

Mitochondria possess two dynamic membranes that envelop a multi-copy genome essential for aerobic energy metabolism. Metazoan mitochondrial DNA is one of the most constrained and simplified genomes ...

We have elected to study this process in the slime mold Physarum polycephalum (Pp), which carries out the widest range of RNA editing events yet described. These changes to mitochondrial RNAs involve ...

1 He and his team administered a short term high fat diet to mice before profiling sperm RNA expression changes and investigating offspring health. They found that the acute high fat diet induced ...