Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

The authors report that LAR inhibits a protein-synthesis step called translocation. Moreover, similar to the mode of action of antibiotics called aminoglycosides, which act at different sites 2 ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...

Amid a surge in drug-resistant bacteria, researchers believe they have discovered a new class of antibiotics, three decades since the last one came to market.

Most of these antibiotics are produced outside the ribosome, the cellular structure responsible for protein synthesis, by specialized peptide synthetases encoded in the genomes of antibiotic ...

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant ...

For the first time in three decades, researchers believe they have identified a new class of antibiotics. Teams at McMaster University in Ontario, Canada and the University of Illinois, Chicago ...

Bacteria can easily evolve, and can quickly gain resistance to drugs. Drug-resistant bacterial infections already cause the deaths of millions ... | Cell And Molecular Biology ...