Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

Further, in validation tasks such as protein pocket design for small molecules like fentanyl and ibuprofen, the effectiveness of PocketGen was confirmed through comparisons with state-of-the-art ...

"The design principles presented here could decisively advance the development of customized protein nanomaterials." More ...

Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and ...

But complete proteome characterization has been hindered by the dynamic range and detection sensitivity of experimental designs, which are not adequate to the very wide range of protein abundances.