By leaving cyclo-oxygenase 1 (COX1)-mediated platelet aggregation and gastric ... of COX2-selective inhibitors might be caused by a prostacyclin and thromboxane imbalance, multiple opposing ...

Reducing the maternal mortality rate due to postpartum haemorrhage depends on the ability of health-care teams to identify pregnant women at higher risk of bleeding, to timely and accurately detect ...

Activated platelets catalyze thromboxane A 2 synthesis in bursts from endogenous platelet arachidonic acid, which is present at a low concentration. Important considerations when investigating ...

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (C.S., K.J.R). Centre for Infection, Immunity ...

Without this process, minor injuries could cause uncontrolled bleeding. Blood clots are made up of two elements: platelets and fibrin. Platelets are cells produced in the bone marrow that travel ...

Chemotherapy attacks all rapidly growing cells, not just cancer cells, and the cells in the bone marrow that are used to replace white blood cells, red blood cells, and platelets are some of the most ...

Patients with pulmonary arterial hypertension (PAH) can develop several complications with the progression of the disease or as a result of hemodynamic imbalance. Some of these complications include ...