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The treatment strategy for congenital adrenal hyperplasia is burdensome and had not changed in more than 70 years until the ...
It is believed that corticosteroids induce their effects on the cell through a glucocorticoid receptor in the cytoplasm ... acting oral corticosteroids (prednisone is prescribed most often ...
Patients with nephrotic syndrome should receive supportive disease management with proteinuria-reducing agents (angiotensin-converting–enzyme inhibitors, angiotensin-receptor blockers ...
The only medication he had been taking was irbesartan, and there was no history of treatment with glucocorticoids ... resmetirom is a thyroid hormone receptor beta–selective agonist that ...
Consequently, the patient was treated with high doses of glucocorticoids, subcutaneous anakinra ... However, the new treatments proved ineffective, and prednisone was reintroduced. At the age of 41, ...
Stopping prophylactic treatment in patients with rheumatic disease on > 12.5 mg/d of prednisone-equivalent corticosteroids ...
Blocking chemokine receptor increases effectiveness of glucocorticoids in multiple myeloma treatment
However, as the disease progresses, many patients develop resistance to glucocorticoids. The research team found that high levels of a protein, the chemokine receptor CCR1, are linked to worse ...
Their study, "A TBX2-Driven Signaling Switch from Androgen Receptor to Glucocorticoid Receptor Confers Therapeutic Resistance in Prostate Cancer," which was published in December 2024 by Oncogene ...
The following is a summary of “Changes in Adrenal Function and Insufficiency Symptoms After Cessation of Prednisolone,” published in the March 2025 issue of JAMA Network Open by Hansen et al.
Long-term glucocorticoid (GC) use among older adults with late-onset rheumatoid arthritis (LORA) remains prevalent, despite its known adverse effects, according to study results published in ACR Open ...
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