The treatment strategy for congenital adrenal hyperplasia is burdensome and had not changed in more than 70 years until the ...

It is believed that corticosteroids induce their effects on the cell through a glucocorticoid receptor in the cytoplasm ... acting oral corticosteroids (prednisone is prescribed most often ...

The following is a summary of “Changes in Adrenal Function and Insufficiency Symptoms After Cessation of Prednisolone,” published in the March 2025 issue of JAMA Network Open by Hansen et al.

RNA sequencing of E18.5 kidneys from glucocorticoid receptor (GR) null mice identified significant reductions in key ciliogenesis-related genes including Ccp110, Cep97, Cep290 and Kif3a. Confocal ...

Behçet's disease (BD) is a systemic large-vessel vasculitis characterized by a wide clinical spectrum including recurrent oral and genital ulcerations, uveitis, and vascular, neurological ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

The CHMP recommendation follows a phase 3 trial of Akeega, called MAGNITUDE, which revealed that the addition of niraparib to Zytiga plus prednisone or prednisolone significantly improved ...

Eight parameters (all blood tests for cytokines or cytokine receptors) were considered to be not available. Tables 4 (remission) and 5 (relapse) depict those items for which RMs achieved a consensus ...