News

GIP receptor shows surprising dual action: Both activation and blockade support weight loss
Drugs that bind to and activate the receptors for the hormones GLP-1 and GIP are effective in the treatment of obesity and diabetes. Surprisingly, active substances are currently being developed that ...
London Evening Standard14d
Ozempic side effects: What are the most concerning consequences of the drug and other weight-loss medicines?
In 2024, roughly 5 per cent of Britons had used an injectable glucagon-like peptide-1 (GLP-1) receptor agonists ... a clinical pharmacist at Oxford Online Pharmacy, some of the most concerning ...
Medical Xpress21d
Novel drug compound offers safer alternative for pain relief by targeting specific receptors
Ph.D., a professor of pharmacodynamics in the UF College of Pharmacy. "Unlike mu receptors, activating delta receptors does not cause respiratory depression. If we can develop drugs that safely ...
Science Daily21d
Researchers identify safer pathway for pain relief
Ph.D., a professor of pharmacodynamics in the UF College of Pharmacy. "Unlike mu receptors, activating delta receptors does not cause respiratory depression. If we can develop drugs that safely ...
Nature21d
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
A second compound, ABT-089, which is a partial agonist at α4β2 nAChRs, was also efficacious in ADHD 172. Similarly, Targacept announced in a press release (Targacept provides update on TC-6499 ...