Tenvie Therapeutics Inc. has divulged NAD(+) hydrolase SARM1 (SAMD2; MyD88-5) inhibitors reported to be useful for the treatment of glaucoma, spinal cord injury, multiple sclerosis, Niemann-Pick ...
Koivunen et al. (pp. 749 and 768) describe the use of phage panning to isolate a cyclic peptide that selectively targets MMPs most closely associated with metastatic potential, and homes to ...
Their previous work identified reversible inhibitors of cJun, but this latest work builds on that by discovering peptides that bind selectively and irreversibly within cells, permanently blocking ...
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