The study presents a valuable finding on the role of cholesterol-binding sites on GLP-1 receptors although the clinical ramifications are unclear and not eminent at this point. Based on the detailed ...

This study presents a valuable finding on the role of cholesterol-binding site on GLP-1 receptors and functionally characterizes the impact of this mutation on receptor behavior in the membrane and ...

Pancreatic islets are clusters of cells within the pancreas. They secrete insulin, the hormone that plays a crucial role in regulating blood sugar levels. In people with type 1 diabetes ...

Present address: Laura Marroquí and Reinaldo S. Dos Santos, Cellular physiology and Nutrition Research Group, Bioengineering Institute, Miguel Hernández University, Elche, 03202, Spain; Spanish ...

Within the pancreas, islet cells secrete insulin to lower blood sugar. However, producing these cells for therapeutic use has proven extremely challenging. While stem cells offer a promising route to ...

In this review, we expose recent advances in the development and use of pancreatic progenitor cells, bone marrow stem cells (MSCs), embryonic stem cells (ESCs) and pluripotent stem cells (PSCs) as ...

The pancreatic islets of Langerhans constitute an endocrine tissue embedded in the exocrine pancreas and represent the sole source of insulin in the human body. Pancreatic islets play a crucial role ...

Use this guideline to guide referrals. If still uncertain about whether a referral is needed, consider contacting a specialist (see the recommendations on the diagnostic process). Consider a review ...