Before the discovery of agents that specifically inhibited osteoclastic bone resorption, there was no effective treatment for Paget's disease. This situation changed with the development for ...

The disease seems to occur in one of two patterns ... right infraorbital fissure, right maxillary bone, lacrimal bone, malar process and zygomatic bone. These bones were soft, suggesting that ...

Dear Reader: The full name of the condition you have been diagnosed with is Paget’s disease of bone. Also known as osteitis deformans, it is a chronic bone disorder. When someone has Paget’s ...

Intensive bisphosphonate treatment does not confer a clinical advantage over treatment of symptoms alone in patients with Paget disease of bone. Findings from a UK study reveal that maintenance of ...

Osteoporosis is common in older adults, especially females and happens due to loss of bone mineral density. Whereas, Paget disease involves thickened and weaker-than-normal bone. The cause is not ...

X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...