Pain Relief Without Addiction: Researchers Develop New Oxytocin-Based Oral Drug
Researchers have developed a new type of oral painkiller for chronic abdominal pain, inspired by the peptide hormone oxytocin ...
EurekAlert!1y
Endogenous opioid peptides system and dose-effect relationship of electroacupuncture (frequency, waveform and intensity) (IMAGE)
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FierceBiotech23d
Tris' next-gen pain drug completes trio of clinical wins, setting up push to FDA
The latest readout saw cebranopadol, a dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist, tested in a phase 3 trial of patients who have undergone toe ...
Business Wire23d
Tris Pharma Announces Positive Results from ALLEVIATE-2 Phase 3 Pivotal Trial for Cebranopadol, an Investigational First-in-Class Oral Dual-NMR Agonist, for the Treatment of ...
About Cebranopadol (TRN-228) Cebranopadol is a first-in-class investigational therapy that targets two key receptors, the nociceptin/orphanin FQ peptide (NOP) and µ-opioid peptide (MOP ...
Hosted on MSN1mon
GLP-1RAs and opioid use disorder: a new frontier in addiction treatment
Glucagon-like peptide receptor agonists (GLP-1RAs ... Now, these drugs are being investigated for a new and unexpected application: opioid use disorder (OUD). Last month, Eli Lilly CEO Dave ...
pharmaphorum4d
Tris cues up filing for non-opioid pain drug on phase 3 win
Cebranopadol – a dual-NMR agonist working on nociceptin/orphanin FQ peptide (NOP) and mu-opioid peptide (MOP) receptors – is a potential first-in-class alternative to opioid analgesics ...
Medscape3d
Use of Pure Opioid Antagonists for Management of Opioid-induced Pruritus
Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...
Wegovy, other weight-loss drugs might help with alcoholism, opioid addiction
Mounjaro or Zepbound appear to help people battle alcoholism and opioid addiction, a new study finds. People taking this ...