"We have identified a key signaling pathway, Rela/NF-kB, that, when blocked, reverses the protumoral function of microglia and activates an immune response against tumors," explains Sánchez ...
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A potential pathway may guide new therapies for inflammatory bowel disease and other inflammatory diseasesDr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...
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