Neuroinflammation significantly contributes to stroke pathophysiology, leading to tissue damage and neurological deficits. Baicalein, a potent 12/15-LOX (12/15-lipoxygenase) inhibitor, demonstrates ...

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

In this review, we summarized key findings of TLR signaling in cardiac hypertrophy. Figure 2. Cardiac hypertrophy mediated by MyD88-dependent and independent TLRs signaling pathways. Numerous specific ...

These effects are recovered by supplying iron via a lysosome-independent pathway. Notably, iron deficiency is sufficient to trigger inflammatory signaling in cultured primary neurons. Using a mouse ...

signaling protein and TLR-MyD88 signaling axis in the oyster (34–36). Moreover, IKK-like and TBK1 genes have been identified in the Pacific oyster (37, 38), as well as a NEMO gene (39). To date, three ...