Multiple myeloma is a type of blood cancer caused by a buildup of abnormal plasma cells in the bone marrow. As the abnormal ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

For decades, the diagnosis of multiple myeloma required evidence of end ... of at least 10% infiltration of clonal plasma cells on bone marrow examination or a biopsy-proven bony or extramedullary ...

1 Multiple myeloma originates in blood plasma cells — a type of cell found in bone marrow that is responsible for making antibodies. When these plasma cells become cancerous, they multiply ...

Novel Bone Marrow Transplant Can Cure Sickle Cell ... New Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma Jan. 14, 2025 — A team of researchers has developed a new ...

Bone marrow transplant ... aplastic or refractory anemia, osteoporosis, multiple myeloma, and a group of blood diseases called Myelodysplastic syndrome.

Doctors use blood and urine tests and imaging tests, such as X-rays or MRIs, to help diagnose multiple myeloma and to guide treatment options. Ultimately, a bone marrow biopsy will confirm the ...

and a multiple myeloma model using human RPMI 8226 cells in immunodeficient NPG mice. The cancer cells were inoculated intratibially into the bone marrow to model tumor growth in bone. Tumor growth ...