Data from the Centers for Disease Control and Prevention show there were about 107,000 drug overdose deaths in the United States in 2023. Of those, about 75%, or 81,000, involved opioids.

Heroin activates a protein found in the brain, spinal cord and gastrointestinal tract called the mu opioid receptor. When activated, these receptors reduce the perception of pain by blocking pain ...

Heroin activates a protein found in the brain, spinal cord and gastrointestinal tract called the mu opioid receptor. When activated, these receptors reduce the perception of pain by blocking pain ...

Amid rising US tariffs on imports from Canada, China, and Mexico over concerns about fentanyl smuggling, we spoke to experts to explain what fentanyl is and why it is so potent.

Anywhere from 2 million to 15 million people use kratom each year. While the substance does induce feelings of mild euphoria, ...

Fentanyl is one of the deadliest drugs on the market, particularly for children, who may accidentally ingest it.

an opioid peptide whose action on the mu-opioid receptor (MOR) stimulates appetite,” they further noted. The team’s newly reported studies indicated that when mice are full and eat sugar ...

"It rapidly crosses the blood-brain barrier and binds opioid mu receptors, causing sedation, analgesia, respiratory depression and apnea. Respiratory depression and apnea lead to inadequate oxygen ...

Trevi Therapeutics has finished enrolling subjects in a trial of investigational Haduvio for treating chronic cough in IPF ...

Peripherally Acting Mu-Opioid Receptor Antagonists, GC-C Agonists, 5-HT4 Receptor Agonists). Geographic Regions/Countries World; United States; Canada; Japan; China; Europe (France; Germany ...