Data from the Centers for Disease Control and Prevention show there were about 107,000 drug overdose deaths in the United States in 2023. Of those, about 75%, or 81,000, involved opioids.

Heroin activates a protein found in the brain, spinal cord and gastrointestinal tract called the mu opioid receptor. When activated, these receptors reduce the perception of pain by blocking pain ...

Amid rising US tariffs on imports from Canada, China, and Mexico over concerns about fentanyl smuggling, we spoke to experts to explain what fentanyl is and why it is so potent.

Oxycodone binds to specific opioid receptors, such as mu, kappa, and delta receptors, to help reduce pain levels. Acetaminophen helps with minor aches and pains while boosting the effects of ...

Cebranopadol – a dual-NMR agonist working on nociceptin/orphanin FQ peptide (NOP) and mu-opioid peptide (MOP) receptors – is a potential first-in-class alternative to opioid analgesics ...

Fentanyl citrate 50mcg/mL; soln for IV or IM inj. Fentanyl is an opioid agonist whose principal therapeutic action is analgesia. The precise mechanism of the analgesic action is unknown although ...

Heroin activates a protein found in the brain, spinal cord and gastrointestinal tract called the mu opioid receptor. When activated, these receptors reduce the perception of pain by blocking pain ...