Selective reduction of OPA1 or MFN1 significantly rescued mitochondrial abnormalities, survival, and locomotor activity, whereas reduction of MFN2 had no effect. RNA sequencing of the pons/medulla ...

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function. Abnormalities in mtDNA are linked to various diseases and are also implicated in ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

The Zika virus builds tiny tunnels, called tunneling nanotubes, to stealthily transport material needed to infect nearby ...

Researchers discovered that Zika virus constructs nanotubes to transport infection across the placental barrier undetected.

When paired with resistance training, a diet rich in protein, complex carbohydrates, and healthy fats can help enhance muscle ...

A recent study has unveiled the pivotal role of Ferroptosis Suppressor Protein 1 (FSP1) in intervertebral disc degeneration ...

Ninetails, a neural network that uses Nanopore Direct RNA sequencing data to identify non-A residues in mRNA poly(A) tails is presented. Particularly non-A of therapeutic, mitochondrial ...