The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that ...

Tissue-specific variability: Evidence that both sequence-dependent and parental allele-specific methylation are frequently unique to specific tissues or cell types, revealing previously ...

Many epigenetics applications leverage the power of single-cell DNA methylation sequencing, which provides unprecedented insight into cellular heterogeneity and gene regulation. Scale Bio offers a ...

Different types of tumors exhibit distinct methylation patterns, which can be analyzed via sequencing. The new method employs ...

The researchers detected 460 regions with parental allele-specific methylation, including hundreds of previously unknown imprinted regions. They also found evidence that both sequence-dependent ...

It also enables the detection of base modifications, such as methylation, which are important for epigenetic studies. Many third-generation sequencing platforms, such as Pacific Biosciences' Single ...

changing their expression without changing the DNA sequence itself. The most common mechanism through which different regulators can cause epigenetic change is DNA methylation. Through methylation, a ...

In this webinar, our expert speakers will discuss how nanopore sequencing has been applied to detect cancer predisposition genes, as well as profiling structural variants, fusions, methylation and ...