Most-abundant zymogen granule proteins. ‡ Different isoforms ... to assess enrichment of ZG membrane proteins and membrane protein topology. Proteomic studies of the pancreatic juice, a rich ...

Few transmembrane proteins have a cylindrical transmembrane ... because of specific interactions but also as a result of membrane topology and viscosity. For example, the ER forms a complex ...

Their work, published in Nature Communications, reveals a mechanism of interdependence of different forms of the cytoskeletal proteins actin ... make the apical membrane—the top of the cell ...