These mysterious droplets, known as biomolecular condensates, solidify when they carry a high proportion of the protein alpha-synuclein, the scientists reported in Science Advances. Clumps of ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Nuclera, the biotechnology company accelerating protein expression and optimization through its benchtop eProtein Discovery™ system, today announced the addition of a new membrane protein workflow to ...

Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study led by the Hospital del Mar Research Institute and published in Nature ...

Finally, molecular docking and molecular dynamics simulation were conducted to evaluate interactions between protein structures encoded by signature ... was selected for fitting the unsigned ...

Moreover, the program can flexibly handle topology features such as virtual sites, and makes it possible to also separately superimpose the tertiary structure restraints of proteins. Topology ...

Researchers say the work is a significant step forward in modeling protein-membrane interactions—resulting in a more accurate and scalable tool for studying cellular membranes, which could have ...

The team combined state-of-the-art neural topology optimization techniques ... Norte and his team are now preparing experiments to push the new membrane sails across distances measured in ...